sequencing by hybridization การใช้

Andrei Mirzabekov initiated the development of the DNA sequencing by hybridization with oligonucleotides : a novel method in 1988.
A collection of maps may be used to reconstruct single-base resolved sequence in a process analogous to sequence reconstruction in sequencing by hybridization.
In the case of magnetic sequencing by hybridization, a set of overlapping tiles is used such that the sequence of each nucleotide is determined by the hybridization of an 8-mer.
The type of sequencing by hybridization described above has largely been displaced by other methods, including sequencing by synthesis, and sequencing by ligation ( as well as pore-based methods ).
Among other results, he contributed ( with Eli Upfal ) a novel approach to DNA Sequencing by Hybridization, achieving sequencing lengths that are the square of what was previously known, which has attracted media coverage.